Researchers for the first time formed a full-fledged human embryo from individual skin cells.
To study congenital diseases, infertility problems, the effects of toxins and viruses on the fruit, scientists use embryos at an early stage of development. However, their work is greatly limited due to the shortage of a suitable material, as well as a number of legal and ethical obstacles. Now the team from the University of Monasha has developed the technology of creating full artificial versions of blastocysts.
For this, the Australian researchers have changed the expression of skin cell genes, reprogramming their kernels so that they behave like building blocks blastocysts. Then they placed them in a jelly-shaped frame, where the modified cells were self-organized into the necessary structure.
Artificial early embryos are not identical natural, since they do not have an external membrane and after several days there are violations of development. These properties in combination of all other structural similarities make them a suitable material for research without guidelines.
The technology will simplify scientists with access to early human embryos, which will accelerate the study of various problems of their development.
Previously, we also reported the development of ceramic ink for a 3D printer that allow you to print
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